NFL Odds, Picks for Week 6: Gruden’s Gone; Look for Bridgewater, Broncos to Repel Raiders

By Ira Kaufman

The NFL’s home-field advantage has been shrinking for a while and Week 6 offers a graphic example.

Of the 13 games on the schedule being played in U.S. stadiums, eight road teams are favored, many by extravagant margins. The Bucs kick off the trend Thursday evening in Philly, where the defending NFL champs are 7-point favorites – even though Tom Brady is nursing an injured right thumb.

This is an intriguing matchup.

Tampa Bay is a road team on a short week and the Eagles may have salvaged their season with a comeback victory in Charlotte.

Running backs have found few holes against the league’s stingiest rush defense, but Jalen Hurts is the first ultra-mobile quarterback the Bucs have faced this season.

The Week 6 slate features a dynamic duel in Cleveland where the Browns are favored by a field goal against the league’s only unbeaten club. Arizona is 5-0, winning shootouts and defensive struggles with equal aplomb, while the Browns come off a bitter 47-42 setback against the surging Chargers.

Speaking of the Chargers, they are 3-point underdogs at Baltimore despite the stellar play of second-year QB Justin Herbert. All he’s done in the past three weeks is throw 11 TD passes without an interception in leading the Chargers to the top of the AFC West.

Fresh off a beatdown of the Chiefs, Buffalo travels to Nashville as a 5 ½-point favorite and it’s easy to see why. The Bills top the league in both scoring offense and scoring defense. Josh Allen averages 274 yards passing and has kept drives going with 17 first downs via scrambles.

While hamstring issues have hampered the production of Titans wide receivers Julio Jones and A.J. Brown, Derrick Henry rolls on, averaging 128 yards on the ground.

The Falcons, Saints, Jets and 49ers have bye weeks.

Here are the Week 6 picks with odds provided by

Eagles (+7) vs. Bucs (Thursday night)

This has the look of a trap game for the Bucs. Philly boasts a solid pass defense and Brady hasn’t had much time to recover from that sore thumb. UPSET SPECIAL: Eagles, 23-20

Jaguars (+3 ½) vs. Dolphins (in London)

Miami is running out of healthy bodies while the Jaguars are eager to show London fans that they are improving. Dolphins, 21-20.

Packers (-4 ½) at Bears

Whenever Aaron Rodgers is in trouble, he looks toward the NFL’s premier wide receiver. Davante Adams always answers the call. Packers, 27-16.

Colts (-9 ½) vs. Texans

Carson Wentz, who threw for 402 yards in that heartbreaking loss to Baltimore, will take out his frustrations on defenseless Houston. Colts, 34-14.

Vikings (-1) at Panthers

Carolina’s young defense will keep this close, but cracks are starting to emerge in Charlotte. Vikings, 24-17.

Chargers (-3) at Ravens

Lamar Jackson is Mr. Excitement, but he can’t throw like Herbert. The Chargers have too many weapons for Baltimore’s pedestrian defense. Chargers, 30-24.

Browns (-3) vs. Cardinals

Nobody is more committed to the run than Cleveland and the Browns have enough impact defenders to challenge Kyler Murray. Browns, 27-21.

Broncos (-3 ½) vs. Raiders

The Jon Gruden era is over, and the Raiders looked lethargic against Chicago. Denver is slumping and this is a statement game for Teddy Bridgewater. Broncos, 23-17.

Cowboys (-4 ½) at Patriots

Dallas has it all going on offense behind Dak Prescott and a powerful ground game. This could be another long year for Bill Belichick. Cowboys, 31-24.

Steelers (-5) vs. Seahawks (Sunday night)

Ben Roethlisberger played well last week, and Seattle’s defense can’t seem to make key stops. Steelers, 27-20.

Washington (-7) vs. Chiefs

Andy Reid is beyond frustrated with KC’s soft defense. Patrick Mahomes may be trying to do too much now. Chiefs, 30-27.

Bengals (-3) at Lions

Joe Burrow is settling in as a consistent quarterback and Cincinnati will get after Jared Goff. Bengals, 34-24.

Giants (+10 ½) vs. Rams

Daniel Jones is dealing with concussion issues but is expected to play. He will find some success against a Rams defense that hasn’t hit its stride. Rams, 27-21.

Bills (-5 ½) at Titans (Monday night)

Buffalo is in perfect harmony heading into Music City., where Derrick Henry is propping up Tennessee. Bills, 33-20.

Last week: 8-7-1 ATS. 11-5 straight up.

Season: 36-27-1 ATS. 43-21 straight up.

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